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Saturday 19 May 2012

Drugs undergo high first pass metabolism in liver:


Mnemonic: V. P Singh Not A Popular P.M
 Verapamil
 Propanolol
 Salbutamol
 Nitroglycerine
 Amitriptyline
 Propoxyphene
 Pethidine
 Methyltestosterone

1 comment:

  1. Does anyone know if the first pass effect is Saturable ?
    Does the amount of Amtriptyline which is converted to Nortriptyline vary dependant upon the size of the dose or of an overdose ?

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